Off-white generally refers to compound colors such as slight yellow or light gray that are very close to white but mixed with trace amounts of other colors. It is mainly used to describe powdery materials whose color has no impact on the quality characteristics of a certain product.
- Application of color measurement of pharmaceutical powders
Pharmaceutical excipients are the basic materials and important components of pharmaceutical preparations and play an important role in the development and production of pharmaceutical preparations at home and abroad. Substances that have been reasonably evaluated for safety and are included in pharmaceutical preparations. In addition to excipients, serving as carriers, and improving stability, pharmaceutical excipients also have important functions such as solubilization, dissolution, and sustained and controlled release. They are important ingredients that may affect the quality, safety, and effectiveness of drugs.
So when this type of pharmaceutical excipients are getting more and more attention, how to ensure that their colors meet the standards?
Below we use a colorimeter to measure and demonstrate how to measure and control the color of additives. The colorimeter adopts ergonomic design; large-capacity data storage and multi-mode color value display; PC software computer data management; USB data connection and output; provides accurate test time settings; can establish the Lab of the standard sample through manual settings * value; suitable for internal and external color evaluation and data management of enterprises
- Steps for color inspection of pharmaceutical powders:
Step 1: Prepare the pharmaceutical additives to be tested first, and weigh the samples to be tested using an electronic balance to prevent measurement errors due to different weights.
Step 2: Compact the pharmaceutical excipients with a powder former to make the surface smooth. Prevent measurement errors caused by light leakage
Step 3: After opening the colorimeter, perform black and white calibration
Step 4: After black and white calibration, press the “Cancel” key to exit, then place the sample, align the standard sample of the medicinal excipient to be tested with the test hole and press the “Test” key. After a “beep” sound, complete the measurement and view the test results;
Step 5: Press the “Enter” key to enter the “Sample Measurement” page. Press the “Test” key again to test. After a “beep” sound, the color difference measurement is completed and the color difference result is displayed.
In recent years, the quality management model of pharmaceutical excipients has been continuously adapted and transformed. With the advent of the era of “strict” drug safety supervision, strengthening the quality control of pharmaceutical excipients is not only a matter for pharmaceutical excipient manufacturers, but also an important responsibility of preparation manufacturers. Therefore, the requirements for color quality control are also higher. Compared with the traditional visual method, the colorimeter has the characteristics of strong objectivity, fast and easy operation, and high repeatability and accuracy. It can help users detect whether the color of pharmaceutical excipients is qualified more quickly and efficiently.
